StrepDB - The Streptomyces Annotation Server
CDS: SCO2785, SCC105.16, desD
Gene: | SCO2785 |
Pritag: | CDS |
Start: | 3038895 |
End: | 3040682 |
Strand: | 1 |
Note: | SCO2785 CAB87222.1 SCC105.16 SCO2785 SCC105.16, hypothetical protein, len: 595 aa; similar to SW:RHSF_RHIME (EMBL:AF110737) Rhizobium meliloti rhizobactin siderophore biosynthesis protein RhsF, 601 aa; fasta scores: opt: 1094 z-score: 1325.6 E(): 0; 32.4% identity in 592 aa overlap and to TR:P94255 (EMBL:U61153) Bordetella bronchiseptica AlcC, 618 aa; fasta scores: opt: 2037 z-score: 2470.2 E(): 0; 51.5% identity in 592 aa overlap |
Product: | conserved hypothetical protein |
db_xref: | GI:7544049, GOA:Q9L069, InterPro:IPR007310, UniProtKB/TrEMBL:Q9L069 |
Conserved Domains
Mouse over the graphic below to see domain descriptions. Click for more details.
About colours in the above displayMarchler-Bauer A et al (2007) CDD: a conserved domain database for interactive domain family analysis. Nucleic Acids Res. 35: D237-40
Publications
- Yang J, Banas VS, Rivera GSM, Wencewicz TA. 2023. Siderophore Synthetase DesD Catalyzes N-to-C Condensation in Desferrioxamine Biosynthesis. ACS chemical biology 18(6):1266-1270. Abstract in PubMed
- Yang J, Banas VS, Patel KD, Rivera GSM, Mydy LS, Gulick AM, Wencewicz TA. 2022. An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD. The Journal of biological chemistry 298(8):102166. Abstract in PubMed
- Hoffmann KM, Kingsbury JS, March NL, Jang Y, Nguyen JH, Hutt MM. 2022. Chemoenzymatic Synthesis of Select Intermediates and Natural Products of the Desferrioxamine E Siderophore Pathway. Molecules (Basel, Switzerland) 27(19):. Abstract in PubMed
- Hoffmann KM, Goncuian ES, Karimi KL, Amendola CR, Mojab Y, Wood KM, Prussia GA, Nix J, Yamamoto M, Lathan K, Orion IW. 2020. Cofactor Complexes of DesD, a Model Enzyme in the Virulence-related NIS Synthetase Family. Biochemistry 59(37):3427-3437. Abstract in PubMed
- Ronan JL, Kadi N, McMahon SA, Naismith JH, Alkhalaf LM, Challis GL. 2019. Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 373(1748):. Abstract in PubMed
- Hagihara R, Katsuyama Y, Sugai Y, Onaka H, Ohnishi Y. 2018. Novel desferrioxamine derivatives synthesized using the secondary metabolism-specific nitrous acid biosynthetic pathway in Streptomyces davawensis. The Journal of antibiotics 71(11):911-919. Abstract in PubMed
- Telfer TJ, Codd R. 2018. Fluorinated Analogues of Desferrioxamine B from Precursor-Directed Biosynthesis Provide New Insight into the Capacity of DesBCD. ACS chemical biology 13(9):2456-2471. Abstract in PubMed
- Telfer TJ, Gotsbacher MP, Soe CZ, Codd R. 2016. Mixing Up the Pieces of the Desferrioxamine B Jigsaw Defines the Biosynthetic Sequence Catalyzed by DesD. ACS chemical biology 11(5):1452-62. Abstract in PubMed
- Rungin S, Indananda C, Suttiviriya P, Kruasuwan W, Jaemsaeng R, Thamchaipenet A. 2012. Plant growth enhancing effects by a siderophore-producing endophytic streptomycete isolated from a Thai jasmine rice plant (Oryza sativa L. cv. KDML105). Antonie van Leeuwenhoek ():page info not available. Abstract in PubMed
- Kadi N, Oves-Costales D, Barona-Gomez F, Challis GL. 2007. A new family of ATP-dependent oligomerization-macrocyclization biocatalysts. Nature chemical biology 3(10):652-6. Abstract in PubMed